I doubt that the sequel novels are considered canon, but I guess that you could still mine them for ideas. Is there anything specific that makes them interesting? If so, I would look for characters, technology and details about L. A..
Of course, Philip K. Dick’s original novel is interesting, even though the characters have slightly different names and the story is set in San Fransisco. I haven’t read the book yet, but it seems to be worth reading. To me, it’s kind of canon. I will most likely use some details.
The comic books are something else. Personally, I don’t like the anime style (what’s noir in a childish style?), but the stories still seem to be part of the official expanded universe. You should be able to draw a lot of stuff out them, I guess. And later this year, an anime TV series will be released as well:
https://en.m.wikipedia.org/wiki/Blade_R ... lack_Lotus
As I’ve said in some of my previous posts here, I see Bladerunner as a strongly genre based franchise. It’s a mix of very early cyberpunk and film noir. Ridley Scott has talked about the Marlowesque style in several interviews. Deckard is an obvious noir figure - basicly a Philip Marlowe put in another era. He’s got the trench coat, the Fedora hat and it’s allways raining. I think the game will need to include much of the rich noir tradition to be really interesting.
Many film noir movies are also set in L. A., so they could be used as an inspiration for developing and expanding the city. Of course, you can’t just copy the 1940s film noir L. A., but some stuff will most likely still be there. For example, the Bradbury Building where J. F. Sebastian lived, was used in several older movies long before Bladerunner. Reusing other locations in the same manner could be really interesting. I would add well known movie locations like Little Tokyo, Mulholland Drive and China Town. They would make sense in the setting.