Hmm, yeah, kind of like how Fantasy Flight did with the different Star Wars game, one playing as Rebels, another as Fringe guys and another as Force users.
But, would you want it set within the same universe?
I would be interested to see how they expand on the ideas and themes of Predator. In particular, I am curious if we might get more insight into where the Predators come from and how they got their tech/built their culture. For instance, the tech the Predators have is so advanced that it would require an entire science/tech/engineering community working on it to create it. But, the bodies of the Predators are animalistic enough. It begs the question of what prompted them to make tech? In the case of humans, from an evolutionary perspective, we became weaker, slower, without claws/teeth, but gained the ability to coordinate better in groups and build tech. However, the Predators seem capable of being powerful hunters with their bodies alone...unless maybe they lived on a planet with some truly horrific beasts, and their increase in intelligence and building of tech was an extended phenotype-style evolutionary arms race against the creatures on their home world. Maybe their tech eventually outstripped their prey on the homeworld, prompting the hunting culture to seek challenge elsewhere.