Have you seen the Ark rules for Mutant Year Zero? I guess the basics are the same, but maybe the Ark is more similar to a space colony. Still, I’m sure you can use the stronghold concept too.
I’m also thinking of the stuff that would be specific for a space colony in the Alien universe. It might for example be corporate connections, corporate representatives, corporate contracts, corporate facilities, and marine protection. Other stuff is more general: power plants, terraforming towers, farming, administration, labs, factories, transports, space port etc. I would also like to see possibilities for creating different kinds of colonies like a mining community, a military base, a farming colony, a penal colony, a research center.
I’ve also been thinking of similar frameworks for other types of locations and organisations: space stations, crime syndicates, large space ships and even xeno nests.